Alterations in the proangiogenic functions of adipose tissue-derived stromal cells isolated from diabetic rats.

@article{Kim2008AlterationsIT,
  title={Alterations in the proangiogenic functions of adipose tissue-derived stromal cells isolated from diabetic rats.},
  author={Hoe Kyu Kim and Yeon Jeong Kim and Jong Tae Kim and Chae H Kwon and Yong Keun Kim and Yong Chan Bae and Dong Heon Kim and Jin Sup Jung},
  journal={Stem cells and development},
  year={2008},
  volume={17 4},
  pages={
          669-80
        }
}
Cardiovascular complications in diabetic patients have been reported to be related to the impaired proangiogenic actions of endothelial progenitor cells. In this study, we investigated the functions of adipose tissue-derived stromal cells (ASCs) in diabetes. We induced type I diabetes in rats by a intraperitoneal injection of 60 mg/kg of streptozotocin (STZ) and type II diabetes by the combined treatment of high fat diet and 45 mg/kg of STZ. Rat ASCs (rASCs) isolated from the adipose tissues in… CONTINUE READING
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