Alterations in the carnitine metabolism in epileptic children treated with valproic acid.

@article{Chung1997AlterationsIT,
  title={Alterations in the carnitine metabolism in epileptic children treated with valproic acid.},
  author={S. W. Chung and J Choi and T. Hyun and Yeongho Rha and Chi-Un Bae},
  journal={Journal of Korean Medical Science},
  year={1997},
  volume={12},
  pages={553 - 558}
}
  • S. ChungJ. Choi C. Bae
  • Published 1 December 1997
  • Medicine, Psychology
  • Journal of Korean Medical Science
Serum concentrations of total carnitine, free carnitine and acylcarnitine were measured in forty-one epileptic patients treated with valproic acid (VPA). Among them, 14 patients were on VPA monotherapy and 27 were on VPA polytherapy. Forty-one age and sex matched healthy normal controls were also evaluated for carnitine metabolism. The mean total and free carnitine were significantly lower in both the VPA monotherapy and polytherapy groups compared with the controls. However, there were no… 

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