Corpus ID: 23027732

Alterations in prejunctional adrenoceptor function in guinea pig and rat vas deferens after chronic ganglionic blockade.

@article{Sax1981AlterationsIP,
  title={Alterations in prejunctional adrenoceptor function in guinea pig and rat vas deferens after chronic ganglionic blockade.},
  author={R. D. Sax and T. Westfall},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1981},
  volume={219 1},
  pages={
          21-6
        }
}
  • R. D. Sax, T. Westfall
  • Published 1981
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
The purpose of the present study was to test the hypothesis that alterations in nerve impulse traffic can influence the activity of substances which act prejunctionally to alter adrenergic neurotransmission. Measurements of the rapid phasic contraction of the isolated rat or guinea-pig vas deferens to short periods of electrical field stimulation were carried out in tissues obtained from saline- or chorisondamine-treated (8 mg/kg twice daily for 5 days) rats and guinea pigs. The alpha-2… Expand
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