Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.

@article{Peterson2008AlterationsIP,
  title={Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.},
  author={Brianna L Peterson and Kyndra C Stovall and Prashant Monian and James Louis Franklin and Brian S. Cummings},
  journal={Chemico-biological interactions},
  year={2008},
  volume={174 3},
  pages={163-76}
}
Specific phospholipids and fatty acids altered during oxidant-induced neuronal cell injury were determined using electrospray ionization mass spectrometry (ESI-MS) and ion trapping. The oxidants hydrogen peroxide (H(2)O(2), 0-1000 microM) and tert-butylhydroperoxide (TBHP, 0-400 microM) induced time- and concentration-dependent increases in reactive oxygen… CONTINUE READING