Alterations in neutrophil production and function at an early stage in the high-fructose rat model of metabolic syndrome.

@article{Tagzirt2014AlterationsIN,
  title={Alterations in neutrophil production and function at an early stage in the high-fructose rat model of metabolic syndrome.},
  author={Madjid Tagzirt and Delphine Corseaux and Louise Pasquesoone and Fr{\'e}d{\'e}ric Mouquet and Charlotte Roma-Lavisse and Alexandre Ung and Rodrigo Lorenzi and Brigitte Jude and Ahmed Elkalioubie and {\'E}ric Van Belle and Sophie Susen and Annabelle Dupont},
  journal={American journal of hypertension},
  year={2014},
  volume={27 8},
  pages={
          1096-104
        }
}
BACKGROUND Although neutrophils are crucially involved in inflammation, they have received only little attention in metabolic syndrome (MetS). We hypothesized that neutrophil infiltration into adipose tissue (AT) may occur at an early stage of MetS, in association with modulation of major functions of neutrophils and of their bone marrow production. METHODS Fifty-six male Sprague-Dawley rats were fed regular (control rats (CRs)) or high-fructose (60%; fructose-fed rats (FFRs)) diets. After 6… CONTINUE READING
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