Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis.

@article{Celone2006AlterationsIM,
  title={Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis.},
  author={Kim A. Celone and Vince D. Calhoun and Bradford C. Dickerson and Alireza Atri and Elizabeth F. Chua and Saul L Miller and Kristina M DePeau and Doreen M. Rentz and Dennis J Selkoe and Deborah Blacker and Marilyn S. Albert and Reisa A. Sperling},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2006},
  volume={26 40},
  pages={10222-31}
}
Memory function is likely subserved by multiple distributed neural networks, which are disrupted by the pathophysiological process of Alzheimer's disease (AD). In this study, we used multivariate analytic techniques to investigate memory-related functional magnetic resonance imaging (fMRI) activity in 52 individuals across the continuum of normal aging, mild cognitive impairment (MCI), and mild AD. Independent component analyses revealed specific memory-related networks that activated or… CONTINUE READING
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