Alterations in mammary-gland blood flow and glucose metabolism in the lactating rat induced by short-term starvation and refeeding.

@article{Jones1984AlterationsIM,
  title={Alterations in mammary-gland blood flow and glucose metabolism in the lactating rat induced by short-term starvation and refeeding.},
  author={R. Gareth Wyn Jones and Dermot H. Williamson},
  journal={Bioscience reports},
  year={1984},
  volume={4 5},
  pages={421-6}
}
Six-hour starvation of lactating rats caused a 75% decrease in mammary-gland lipogenesis. The inhibition of lipogenesis was accompanied by a 45% decrease of blood flow to the mammary gland and a 60% decrease in glucose uptake. Within 2 h of refeeding, lipogenesis and glucose uptake by the gland increased to fed values though blood flow to the gland remained at only 63% of that in the fed state. It is concluded that blood flow, and hence substrate supply, is not a rate-limiting factor for… CONTINUE READING