Alterations in intracellular messengers mobilized by gonadotropin-releasing hormone in an experimental ovarian tumor.

@article{ChamsonReig1999AlterationsII,
  title={Alterations in intracellular messengers mobilized by gonadotropin-releasing hormone in an experimental ovarian tumor.},
  author={A. Chamson-Reig and O. Pignataro and C. Libertun and V. Lux-Lantos},
  journal={Endocrinology},
  year={1999},
  volume={140 8},
  pages={
          3573-80
        }
}
Cells derived from an experimental luteinized ovarian tumor are more sensitive to GnRH endocrine action than control luteal cells. In an attempt to understand the possible causes of the differential sensibility to GnRH action, we examined the number and affinity of GnRH receptors and the second messenger response to GnRH stimulation in both tissues. For GnRH receptor studies membranes were obtained from 4- to 6-week-old ovarian tumors (luteoma) and ovaries from prepubertal rats treated with 25… Expand
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Development of an experimental ovarian tumor: immunocytochemical analysis.
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