Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin.

  title={Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin.},
  author={Carol Sabourin and John P. Petrali and Robert P. Casillas},
  journal={Journal of biochemical and molecular toxicology},
  volume={14 6},
Cutaneous exposure to sulfur mustard (bis(2-chloroethyl) sulfide, HD), a chemical warfare agent, produces a delayed inflammatory skin response and severe tissue injury. Despite defined roles of inflammatory cytokines produced or released in response to skin-damaging chemicals, in vivo cytokine responses associated with HD-induced skin pathogenesis are not well understood. Additionally, there is little information on the in vivo temporal sequence of gene expression of cytokines postexposure to… CONTINUE READING


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