Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues.

@article{Weeraratna2007AlterationsII,
  title={Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues.},
  author={Ashani T Weeraratna and Audrey N Kalehua and Isoke Deleon and Dorothy Bertak and Gregory W. Maher and Michael S. Wade and Ana Lustig and Kevin G. Becker and William Kenneth Wood and Douglas G. Walker and Thomas Gerald Beach and Dennis D. Taub},
  journal={Experimental cell research},
  year={2007},
  volume={313 3},
  pages={450-61}
}
Microarray technology was utilized to isolate disease-specific changes in gene expression by sampling across inferior parietal lobes of patients suffering from late onset AD or non-AD-associated dementia and non-demented controls. Primary focus was placed on understanding how inflammation plays a role in AD pathogenesis. Gene ontology analysis revealed that the most differentially expressed genes related to nervous system development and function and neurological disease followed by genes… CONTINUE READING