Alterations in crypt cell populations in the small intestine as an early toxic response to sub-acute ethanol administration

Crypt cell production was examined in young male rats (Sprague-Dawley) given 1, 5 or 15% ethanol in their drinking water for up to 14 days. Ethanol 1 and 5% did not influence food and liquid consumption and growth was similar to that seen in control animals given tap water only to drink. Animals given 15% ethanol exhibited a significant reduction in food… CONTINUE READING