Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD.

@article{Matthan2009AlterationsIC,
  title={Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD.},
  author={Nirupa R. Matthan and Michael J. Pencina and Jane M LaRocque and Paul F Jacques and Ralph B. D'Agostino and Ernst J. Schaefer and Alice H Lichtenstein},
  journal={Journal of lipid research},
  year={2009},
  volume={50 9},
  pages={1927-35}
}
Data is limited on measures influencing cholesterol homeostasis in subjects at high risk of developing cardiovascular disease (CVD) relative to established risk factors. To address this, we quantified circulating indicators of cholesterol homeostasis (plasma phytosterols and cholesterol precursor concentrations as surrogate measures of cholesterol absorption and synthesis, respectively) in Framingham Offspring Study Cycle-6 participants diagnosed with established CVD and/or >or=50% carotid… CONTINUE READING