Alterations in cardiac beta-adrenergic receptors in chagasic mice and their association with circulating beta-adrenoceptor-related autoantibodies.

@article{SterinBorda1999AlterationsIC,
  title={Alterations in cardiac beta-adrenergic receptors in chagasic mice and their association with circulating beta-adrenoceptor-related autoantibodies.},
  author={Leonor Sterin-Borda and Gabriela Gorelik and Miriam Postan and Stella Maris Gonz{\'a}lez Cappa and Enri Borda},
  journal={Cardiovascular research},
  year={1999},
  volume={41 1},
  pages={116-25}
}
OBJECTIVE Cardiac tissue from chagasic mice was studied to evaluate the expression and biological activity of beta-adrenoceptors in association with circulating beta-adrenoceptor-related autoantibodies. METHODS BALB/c inbred mice that were either treated or not treated with atenolol (2.5 mg/kg) and infected or not infected with 1 x 10(4) trypomastigotes (CA-1 strain) were sacrificed weekly up to week nine. Morphological, binding and contractility studies were performed on the four different… CONTINUE READING

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