Alterations in biliary motility correlate with increased gallbladder prostaglandin synthesis in early cholelithiasis in prairie dog

@article{Chapman1989AlterationsIB,
  title={Alterations in biliary motility correlate with increased gallbladder prostaglandin synthesis in early cholelithiasis in prairie dog},
  author={William C. Chapman and George A. Peterkin and PhD Wayne W. LaMorte and Dr. Lester F. Williams},
  journal={Digestive Diseases and Sciences},
  year={1989},
  volume={34},
  pages={1420-1424}
}
Abnormal biliary motility has been observed in humans with gallstones and in animal models; however, the mechanism by which these abnormalities occur remains unknown. In this study we investigated the relationship between cholesterol gallstone formation, changes in biliary motility, and rates of gallbladder prostaglandin synthesis in prairie dogs receiving a 0.34% cholesterol diet for two, four, or six weeks. Gallstones did not occur until four weeks, when the incidence was 14%; after six weeks… CONTINUE READING
7 Citations
24 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…