Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy.

@article{Hava2006AlterationsIB,
  title={Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy.},
  author={Golan Hava and Lev Vered and Mazar Yael and Hallak Mordechai and Huleihel Mahoud},
  journal={Developmental psychobiology},
  year={2006},
  volume={48 2},
  pages={162-8}
}
Maternal intrauterine inflammation during pregnancy poses a major threat of neurodevelopmental brain damage in offspring and may cause poor cognitive and perceptual outcomes. In mice, we have previously shown that maternal inflammation induced by lipopolysaccharide (LPS) at gestation day 17th increased the levels of the pro-inflammatory cytokine IL-6 in the fetal brain. In this study, we used the same system and examined the effect of short, systemic maternal inflammation on anxiety and social… CONTINUE READING

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