Alterations in amygdala functional connectivity reflect early temperament.

  title={Alterations in amygdala functional connectivity reflect early temperament.},
  author={Amy Krain Roy and Brenda E Benson and Kathryn Amey Degnan and Koraly E. P{\'e}rez-Edgar and Daniel S. Pine and Nathan A. Fox and Monique Ernst},
  journal={Biological psychology},
Behavioral inhibition (BI) is a temperament identified early in life that is associated with increased risk for anxiety disorders. Amygdala hyperresponsivity, found both in behaviorally inhibited and anxious individuals, suggests that amygdala dysfunction may represent a marker of anxiety risk. However, broader amygdala networks have not been examined in individuals with a history of childhood BI. This study uses resting state fMRI to assess amygdala intrinsic functional connectivity (iFC) in… CONTINUE READING
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