Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease.

@article{Fabbrini2008AlterationsIA,
  title={Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease.},
  author={Elisa Fabbrini and Balsamanirina S Mohammed and Faidon Magkos and Kevin M. Korenblat and Bruce W. Patterson and S. Klein},
  journal={Gastroenterology},
  year={2008},
  volume={134 2},
  pages={424-31}
}
BACKGROUND & AIMS Steatosis in patients with nonalcoholic fatty liver disease (NAFLD) is due to an imbalance between intrahepatic triglyceride (IHTG) production and export. The purpose of this study was to evaluate TG metabolism in adipose tissue and liver in NAFLD. METHODS Fatty acid, VLDL-TG, and VLDL-apolipoprotein B-100 (apoB100) kinetics were assessed by using stable isotope tracers in 14 nondiabetic obese subjects with NAFLD (IHTG, 22.7% +/- 2.0%) and 14 nondiabetic obese subjects with… CONTINUE READING
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