Alterations in System xc − Expression in the Retina of Type 1 Diabetic Rats and the Role of Nrf2

Abstract

Nrf2 (nuclear factor erythroid 2-related factor 2), a transcription factor that controls expression of several proteins that are related to cellular antioxidant capacity, such as the subunit xCT of the system xc −, is dysregulated in diabetes. Recently, it was described that system xc − is decreased in the retina after 3 weeks of diabetes. So, in the… (More)
DOI: 10.1007/s12035-018-0961-8

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