Alterations in Plasma and Tissue Acetylcholinesterase Activity Following Repeated Oral Exposure of Chlorpyrifos Alone and in Conjunction with Fluoride in Wistar Rats

@article{Baba2013AlterationsIP,
  title={Alterations in Plasma and Tissue Acetylcholinesterase Activity Following Repeated Oral Exposure of Chlorpyrifos Alone and in Conjunction with Fluoride in Wistar Rats},
  author={Naseer Ahmad Baba and Rajinder K. Raina and Pawan Kumar Verma and M. Chand Sultana},
  journal={Proceedings of the National Academy of Sciences, India Section B: Biological Sciences},
  year={2013},
  volume={84},
  pages={969-972}
}
Concurrent exposures of more than one environmental contaminants are commonly encountered by human beings and animals. This study investigated the effect of chlorpyrifos alone and in conjunction with fluoride on plasma and tissue acetylcholinesterase (AChE) activity in wistar rats. Fluoride at 1 or 10 ppm in drinking water produced significant (P < 0.05) inhibition of AChE activity in a dose dependant manner and inhibition was maximum in brain (26.39 %) and least in heart (10.23 %). Similarly… CONTINUE READING
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In vivo chlorpyrifos induced oxidative stress: attenuation by antioxidant vitamins

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