Alterations in Janus Kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) Signaling in Patients With End-Stage Dilated Cardiomyopathy

@article{Podewski2003AlterationsIJ,
  title={Alterations in Janus Kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) Signaling in Patients With End-Stage Dilated Cardiomyopathy},
  author={E. Podewski and D. Hilfiker-Kleiner and A. Hilfiker and H. Morawietz and A. Lichtenberg and K. Wollert and H. Drexler},
  journal={Circulation: Journal of the American Heart Association},
  year={2003},
  volume={107},
  pages={798-802}
}
  • E. Podewski, D. Hilfiker-Kleiner, +4 authors H. Drexler
  • Published 2003
  • Medicine
  • Circulation: Journal of the American Heart Association
  • Background—Experimental studies indicate that interleukin-6 (IL-6)–related cytokines, signaling via the shared receptor gp130, Janus kinases (JAKs), and signal transducers and activators of transcription (STATs), provide a critical cardiomyocyte survival pathway in vivo. Little is known about the activation of this signaling pathway in the myocardia of patients with end-stage dilated cardiomyopathy (DCM). Methods and Results—We performed a comprehensive expression and activation analysis of IL… CONTINUE READING
    Survival pathways in hypertrophy and heart failure: The gp130-STAT3 axis
    119
    Survival pathways in hypertrophy and heart failure: The gp130-STAT3 axis
    163

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 21 REFERENCES