Alterations in Ionic Currents and Relation to Contractile Dysfunction with Severe Cardiac Hypertrophy and Failure

Abstract

Myocardial dysfunction with severe cardiac hypertrophy and congestive heart failure is associated with abnormalities in myocyte action potential morphology, and consequently, trans-sarcolemmal ionic currents. Determination of the primary ionic current or event which contributes to myocardial contractile dysfunction is an area of active research. This review… (More)
DOI: 10.1023/A:1009899502335

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@article{Mukherjee2004AlterationsII, title={Alterations in Ionic Currents and Relation to Contractile Dysfunction with Severe Cardiac Hypertrophy and Failure}, author={Rupak D Mukherjee and Francis G. Spinale}, journal={Heart Failure Reviews}, year={2004}, volume={4}, pages={319-327} }