Alterations in CNS activity induced by botulinum toxin treatment in spasmodic dysphonia: an H215O PET study.

@article{Ali2006AlterationsIC,
  title={Alterations in CNS activity induced by botulinum toxin treatment in spasmodic dysphonia: an H215O PET study.},
  author={S Omar Ali and M Christella L G D Thomassen and Geralyn M. Schulz and Lara A Hosey and Mary Varga and Christy L. Ludlow and Allen R. Braun},
  journal={Journal of speech, language, and hearing research : JSLHR},
  year={2006},
  volume={49 5},
  pages={1127-46}
}
Speech-related changes in regional cerebral blood flow (rCBF) were measured using H(2)(15)O positron-emission tomography in 9 adults with adductor spasmodic dysphonia (ADSD) before and after botulinum toxin (BTX) injection and 10 age- and gender-matched volunteers without neurological disorders. Scans were acquired at rest and during production of continuous narrative speech and whispered speech. Speech was recorded during scan acquisition for offline quantification of voice breaks, pitch… CONTINUE READING

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