Alterations in Alzheimer's disease-associated protein in Alzheimer's disease frontal and temporal cortex.

@article{Bissette1991AlterationsIA,
  title={Alterations in Alzheimer's disease-associated protein in Alzheimer's disease frontal and temporal cortex.},
  author={Garth Bissette and William H. Smith and Kenneth C. Dole and Barbara Crain and Hossein Ghanbari and Bruce E. Miller and Charles B. Nemeroff},
  journal={Archives of general psychiatry},
  year={1991},
  volume={48 11},
  pages={1009-12}
}
Alzheimer's disease (AD)-associated protein is present in brain and cerebrospinal fluid of patients with AD but not in adult, nondemented, normal controls. This protein may represent an abnormal epitope of the "tau" microtubule-associated protein and has been detected before the appearance of senile plaques and neurofibrillary tangles. The amount of AD… CONTINUE READING