Alteration of the repressor activity of MarR, the negative regulator of the Escherichia coli marRAB locus, by multiple chemicals in vitro.

@article{Alekshun1999AlterationOT,
  title={Alteration of the repressor activity of MarR, the negative regulator of the Escherichia coli marRAB locus, by multiple chemicals in vitro.},
  author={Michael N. Alekshun and S. Berville Levy},
  journal={Journal of bacteriology},
  year={1999},
  volume={181 15},
  pages={
          4669-72
        }
}
MarR negatively regulates expression of the multiple antibiotic resistance operon (marRAB) in Escherichia coli. In this study, it was demonstrated that sodium salicylate, plumbagin, 2, 4-dinitrophenol, and menadione-inducers of the marRAB operon in whole cells-all interfered with the repressor activity of MarR in vitro. It is proposed that these compounds can interact directly with MarR to affect its repressor activity. 

Citations

Publications citing this paper.
SHOWING 1-10 OF 72 CITATIONS

FILTER CITATIONS BY YEAR

2000
2019

CITATION STATISTICS

  • 12 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

  • 33% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 30 REFERENCES

Similar Papers

Loading similar papers…