Alteration of the product specificities of prenyltransferases by metal ions.

@article{Ohnuma1993AlterationOT,
  title={Alteration of the product specificities of prenyltransferases by metal ions.},
  author={Shin-ichi Ohnuma and Takako Koyama and Kyozo Ogura},
  journal={Biochemical and biophysical research communications},
  year={1993},
  volume={192 2},
  pages={
          407-12
        }
}
Effect of several kinds of metal ions on the chain-length distribution of reaction products of polyprenyl diphosphate synthases was investigated. In the presence of Co2+ or Mn2+ octaprenyl-, solanesyl- and decaprenyl diphosphate synthases gave a variety of polyprenyl products with the longest chains being shifted by one or two isoprene units longer than those of the products formed in the presence of Mg2+. Thus octaprenyl diphosphate synthase became to give solanesyl (C45) and decaprenyl (C50… 
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