Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury.

@article{Okonkwo1998AlterationOT,
  title={Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury.},
  author={David O. Okonkwo and Edward H. Pettus and Junta Moroi and John Theodore Povlishock},
  journal={Brain research},
  year={1998},
  volume={784 1-2},
  pages={1-6}
}
Traumatic injury evokes two characteristic forms of focal axonal injury, one of which involves focal perturbation of axolemmal permeability associated with rapid compaction of the underlying axonal neurofilament lattice and microtubular loss. In this process, the neurofilament sidearms have been the subject of intense scrutiny in relation to their role in this NF compaction, with the suggestion that the sidearms, thought to maintain interfilament distance, are proteolytically cleaved and… CONTINUE READING
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