Alteration of the expression of adenosine triphosphate-binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis.

@article{Kamisako2005AlterationOT,
  title={Alteration of the expression of adenosine triphosphate-binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis.},
  author={Toshinori Kamisako and Hiroshi Ogawa},
  journal={Journal of gastroenterology and hepatology},
  year={2005},
  volume={20 9},
  pages={1429-34}
}
BACKGROUND AND AIM Multidrug resistance protein 2 (Mrp2), Mrp3, adenosine triphosphate-binding cassette transporter g5 (Abcg5) and adenosine triphosphate-binding cassette transporter g8 (Abcg8) have been identified as bile acid or cholesterol transporter in the enterocytes as well as hepatocytes. The purpose of the present study was to evaluate intestinal and hepatic adenosine triphosphate-binding cassette transporter expressions during cholestasis. METHODS Experiment 1: Rats were subjected… CONTINUE READING