Alteration of the PAC1 Receptor Expression in the Basal Ganglia of MPTP-Induced Parkinsonian Macaque Monkeys

Abstract

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a well-known neuropeptide with strong neurotrophic and neuroprotective effects. PACAP exerts its protective actions via three G protein-coupled receptors: the specific Pac1 receptor (Pac1R) and the Vpac1/Vpac2 receptors, the neuroprotective effects being mainly mediated by the Pac1R. The… (More)
DOI: 10.1007/s12640-017-9841-7

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Cite this paper

@article{Feher2017AlterationOT, title={Alteration of the PAC1 Receptor Expression in the Basal Ganglia of MPTP-Induced Parkinsonian Macaque Monkeys}, author={Michael Feher and Bal{\'a}zs Gaszner and Anton H. Tamas and Ana Luisa Gil-Mart{\'i}nez and Emiliano Fern{\'a}ndez-Villalba and Mar{\'i}a Trinidad Herrero and Dora Reglodi}, journal={Neurotoxicity Research}, year={2017}, pages={1-14} }