Alteration of stratum corneum ceramide profiles in spontaneous canine model of atopic dermatitis.

@article{Yoon2011AlterationOS,
  title={Alteration of stratum corneum ceramide profiles in spontaneous canine model of atopic dermatitis.},
  author={Ji-seon Yoon and Koji Nishifuji and Ako Sasaki and Kaori Ide and Junko Ishikawa and Toru Yoshihara and Toshiroh Iwasaki},
  journal={Experimental dermatology},
  year={2011},
  volume={20 9},
  pages={
          732-6
        }
}
Ceramides (CERs) in the stratum corneum (SC) are thought to play a key role in cutaneous barrier function. It has been reported that human SC contains 11 free CER classes and that their profiles are altered in humans with atopic dermatitis (AD). Although decreased proportions of free CERs or quantities of protein-bound CERs in the SC have been reported in dogs with AD, the overall profile of CERs in the canine SC has not been fully elucidated. The aim of this study was thus to investigate the… CONTINUE READING
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Citations

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