Alteration of somatosensory evoked potentials in response to global ischemia.

@article{Lesnick1984AlterationOS,
  title={Alteration of somatosensory evoked potentials in response to global ischemia.},
  author={J E Lesnick and John J. Michele and Frederick A. Simeone and S. Defeo and Frank A. Welsh},
  journal={Journal of neurosurgery},
  year={1984},
  volume={60 3},
  pages={
          490-4
        }
}
The somatosensory evoked potential (SEP) measured in response to median nerve stimulation was correlated with cortical and white matter cerebral blood flow (CBF), adenosine triphosphate (ATP), and lactate levels in 14 cats subjected to graded hemorrhagic hypotension following bilateral carotid artery ligation. Three additional cats served as controls. Regional CBF was determined by the hydrogen clearance method, and the time for conduction of the sensory stimulus from the thalamus to the cortex… 
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79 Citations
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Results Citations
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79 Citations

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Comparison of the somatosensory evoked potential and the direct cortical response following severe incomplete global ischemia: selective vulnerability of the white matter conduction pathways.
TLDR
In this model of global ischemia, abolition of the cortical SEP is due to a block of stimulus conduction in white matter projection pathways and a hypothesis to explain the observed metabolic changes is presented and correlation is made to clinical situations.
Cerebral blood flows and tissue oxygen levels associated with maintenance of the somatosensory evoked potential and cortical neuronal activity in focal ischemia.
TLDR
In all animals occlusion resulted in a predictable extended latency change and a variable amplitude response of the cortical component of the contralaterally recorded somatosensory evoked potentials.
Failure of the somatosensory evoked potential following middle cerebral artery occlusion and high-grade ischemia in the cat--effects of hemodilution.
TLDR
Significant increases in the contralateral hemisphere gray matter CBF occurred following hemodilution while the latency of the cortical component of the SSEP in this same hemisphere was significantly extended.
Differentiation between cortical and subcortical lesions following focal ischemia in cats by multimodality evoked potentials
Reversibility of transient focal cerebral ischemia evaluated by somatosensory evoked potentials in cats.
Evoked potentials in cerebral ischemia.
TLDR
This issue of Stroke highlights the use of short latency somatosensory evoked potentials (SEPs) to quantify neuronal dysfunction in models of cerebral ischemia and to study stroke patients, and it is important to understand the technical difficulties, to appreciate the care required for a dependable result, and to recognize the limitations on interpretation.
Correlation between somatosensory evoked potentials and neuronal ischemic changes following middle cerebral artery occlusion.
TLDR
It is demonstrated that the disappearance of the SEP and their failure to recover correlate with the extent and degree of histological cerebral ischemia.
Changes in somatosensory evoked potentials following forebrain ischemia in the gerbils: effects of felbamate
TLDR
Felbamate administration at the dose of 150 mg kg‐1 immediately after recirculation was shown to ameliorate neurophysiological recovery following cerebral ischemia and reduce SEP amplitude during bilateral carotid occlusion.
Extended latency of the cortical component of the somatosensory-evoked potential accompanying moderate increases in cerebral blood flow during systemic hypoxia in cats
Correlation between somatosensory-evoked potentials and magnetic resonance imaging of focal cerebral ischemia in cats.
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References

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TLDR
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