Alteration of pulmonary function in intravenous drug abusers. Prevalence, severity, and characterization of gas exchange abnormalities.

@article{Overland1980AlterationOP,
  title={Alteration of pulmonary function in intravenous drug abusers. Prevalence, severity, and characterization of gas exchange abnormalities.},
  author={E. S. Overland and Andrew James Nolan and P. Hopewell},
  journal={The American journal of medicine},
  year={1980},
  volume={68 2},
  pages={
          231-7
        }
}
We examined the influence of chronic intravenous drug abuse on respiratory function in 512 consecutive drug addicts by obtaining respiratory histories, pulmonary function tests and chest roentgenograms. Two hundred and fourteen (42 per cent) had carbon monoxide-diffusing capacities (DLCO) of less than 75 per cent predicted (mean 65.7 per cent), and in 38 per cent reduced DLCO was the sole pulmonary function test abnormality. Obstructive lung disease attributed to asthma or chronic bronchitis… CONTINUE READING
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