Alteration of immunoglobulin-bearing lymphoma cells by fixation.

  title={Alteration of immunoglobulin-bearing lymphoma cells by fixation.},
  author={Roger Warnke},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  volume={27 8},
  • Roger Warnke
  • Published 1979 in
    The journal of histochemistry and cytochemistry…
Four large cell lymphomas known to be monoclonal B-cell proliferations were studied with immunofluorescent and immunohistochemical methods for the detection of kappa- and lambda-light chains. Frozen sections of lymphoma tissues as well as formalin and B-5-fixed tissues embedded in paraffin were studied. Both immunofluorescent and immunohistochemical methods gave similar results on frozen sections; however, a number of discrepancies were noted between the results obtained on fixed tissues and… CONTINUE READING