Alteration of glutamyltranspeptidase binding proteins in postmortem brains of heroin addicts.

@article{Hashimoto1996AlterationOG,
  title={Alteration of glutamyltranspeptidase binding proteins in postmortem brains of heroin addicts.},
  author={Eikichi Hashimoto and Lutz Fr{\"o}lich and Hidetoshi Ozawa and Toshikazu Saito and S. Shichinohe and Naohiko Takahata and Peter Franz Riederer},
  journal={Alcoholism, clinical and experimental research},
  year={1996},
  volume={20 9 Suppl},
  pages={301A-304A}
}
Glutamyltranspeptidase binding (G) proteins play an important role in intracellular signal transduction downstream from many receptors, including opioid receptors. Moreover, it was recently reported that the beta-subunits of G proteins, in addition to the alpha-subunits, regulate effector pathways. In this study, membrane G protein immunoreactivity was estimated by Western blotting with polyclonal antibodies (RM/1, AS/7, GC/2, QL, and SW/1) against specific G proteins (G alpha S, G alpha i-1,2… CONTINUE READING