Alteration of extracellular collagen matrix in the myocardium of canines infected with Dirofilaria immitis.

@article{Wang2005AlterationOE,
  title={Alteration of extracellular collagen matrix in the myocardium of canines infected with Dirofilaria immitis.},
  author={J Wang and K R Tung and Chiu-Chen Huang and Cheng-Hung Lai},
  journal={Veterinary parasitology},
  year={2005},
  volume={131 3-4},
  pages={261-5}
}
The heart consists of cardiocytes and the interstitial extracellular matrix (ECM), which is made up mainly of collagens. The ECM has been suggested to be important in maintaining the structure and function of the heart. This investigation attempted to elucidate the changes in the ECM collagens in the hearts of canines with dirofilariasis. The ECM collagen fibrils of the heart are grouped into endomysial struts, epimysial weaves, and perimysial coils. In the present study, we used the modified… CONTINUE READING