Alteration of electrical and motor activity of human and dog rectum by diphenylhydantoin


The present in vitro study on isolated colon strips in humans and dogs indicates that diphenylhydantoin acts both on neuromuscular junctions and directly on smooth muscle. Diphenylhydantoin (DPH) opposes the action of acetylcholine (ACH) and 5-hydroxytryptamine (5-HT) on neuromuscular junctions and exerts its relaxing effect on postganglionic or… (More)
DOI: 10.1007/BF01071990


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