Alteration of balance between myeloid dendritic cells and plasmacytoid dendritic cells in peripheral blood of patients with asthma.

@article{Matsuda2002AlterationOB,
  title={Alteration of balance between myeloid dendritic cells and plasmacytoid dendritic cells in peripheral blood of patients with asthma.},
  author={Hiroyuki Matsuda and Takafumi Suda and Hideo Hashizume and Koushi Yokomura and Kazuhiro Asada and Kenichiro Suzuki and Kingo Chida and Hirotoshi Nakamura},
  journal={American journal of respiratory and critical care medicine},
  year={2002},
  volume={166 8},
  pages={1050-4}
}
Asthma, a well-known helper T cell Type 2 (Th2)-mediated disease, has a polarized immune response toward a Th2 phenotype. However, the factors causing the Th2 polarization remain to be fully determined in this disease. Dendritic cells (DCs) are the most potent antigen-presenting cells that play a central role in initiating the primary immune response. In human blood, two functional distinct subsets of DCs, myeloid DCs and plasmacytoid DCs, have been identified. Myeloid DCs (mDCs) and… CONTINUE READING

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