Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.

@article{Asaka1994AlterationOA,
  title={Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.},
  author={Masahiro Asaka and Toshio Kimura and Takashi Meguro and Mototsugu Kato and Mayumi Kudo and Takashi Miyazaki and Elliot Alpert},
  journal={Journal of clinical laboratory analysis},
  year={1994},
  volume={8 3},
  pages={144-8}
}
We studied the alteration of aldolase isozymes in the serum and tissues of patients with cancer and other diseases using radioimmunoassays specific for aldolase A, B, and C subunits. Aldolase B was predominantly found in adult liver, where aldolase A and C were distinctly low. Aldolase A and B showed almost the same concentration in fetal liver, while in neonatal liver aldolase B protein concentrations were much higher than aldolase A. In contrast, aldolase A was the predominant isozyme found… CONTINUE READING
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