Alteration of adipokines during peripheral blood stem cell mobilization induced by granulocyte colony‐stimulating factor

@article{Tanaka2009AlterationOA,
  title={Alteration of adipokines during peripheral blood stem cell mobilization induced by granulocyte colony‐stimulating factor},
  author={Y. Tanaka and T. Yujiri and M. Tanaka and Noriyuki Mitani and A. Tanimura and Y. Tanizawa},
  journal={Journal of Clinical Apheresis},
  year={2009},
  volume={24}
}
  • Y. Tanaka, T. Yujiri, +3 authors Y. Tanizawa
  • Published 2009
  • Medicine
  • Journal of Clinical Apheresis
  • Adipokines, soluble mediators produced by adipocytes, have been shown to play a role in various physiological and pathological conditions. We investigated the involvement of adipokines in granulocyte colony‐stimulating factor (G‐CSF)‐induced mobilization of hematopoietic stem cells in 21 healthy donors. We found that serum visfatin and resistin levels, but not leptin and adiponectin levels, were significantly elevated by G‐CSF treatment. G‐CSF treatment activated signaling proteins like… CONTINUE READING
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