Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis.

@article{Fenoglio2011AlterationOT,
  title={Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis.},
  author={Daniela Fenoglio and Florinda Battaglia and Alessia Parodi and Silvia Stringara and Simone Negrini and Nicoletta Panico and Marta Rizzi and Francesca Kalli and Giuseppina Conteduca and Massimo Ghio and Raffaele De Palma and Francesco Indiveri and Gilberto Filaci},
  journal={Clinical immunology},
  year={2011},
  volume={139 3},
  pages={
          249-57
        }
}
Aim of the study has been to understand the relationship between TH17 and Treg cell subsets in patients affected with systemic sclerosis (SSc). Phenotypes and functions of Th17 and Treg cell subsets were analyzed in a series of 36 SSc patients. Th17 cell concentration in the peripheral blood was found to be increased in SSc patients with respect to healthy controls independently from type or stage of disease. After PBMC stimulation with a polyclonal stimulus or Candida albicans antigens the… CONTINUE READING

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