Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patients with esophageal squamous cell carcinoma.

@article{Zhang2013AlterationOH,
  title={Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patients with esophageal squamous cell carcinoma.},
  author={Xiaoying Zhang and Aifen Lin and J-g Zhang and W-G Bao and D Xu and Y-Y Ruan and W Yan},
  journal={International journal of cancer},
  year={2013},
  volume={132 1},
  pages={82-9}
}
Alteration of human leukocyte antigen (HLA) expression, such as decreased HLA I (HLA-A, -B and -C) antigens and elevated nonclassical HLA I antigens (HLA-E, -F and -G), was reported to have an unfavorable prognosis in various cancers. In our study, HLA-F expression in 105 primary esophageal squamous cell carcinoma (ESCC) lesions and 62 case-matched adjacent normal tissues, and HLA I antigens among 68 cases were analyzed by immunohistochemistry. Data revealed that HLA-F expression was observed… CONTINUE READING
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