Alteration of CD44 and cadherins expression: possible association with augmented aggressiveness and invasiveness of endometrial carcinoma

@article{Leblanc2000AlterationOC,
  title={Alteration of CD44 and cadherins expression: possible association with augmented aggressiveness and invasiveness of endometrial carcinoma},
  author={Marc Leblanc and Christophe Poncelet and Danilo Sone Soriano and Francine Walker-Combrouze and Patrick Mad{\'e}l{\'e}nat and Jean Yves Scoazec and Evangelia Darai},
  journal={Virchows Archiv},
  year={2000},
  volume={438},
  pages={78-85}
}
Cadherins and CD44 isoforms are transmembrane glycoproteins with diverse functions in cell–cell and cell–matrix interactions and may be a determinant of invasive and metastatic behavior in carcinomas. The immunohistochemical expression of cadherins and CD44 in tissue samples from 15 normal endometrium and 33 endometrial adenocarcinomas were examined. The immunohistochemical analysis was performed using the monoclonal antibody HECD-1 against E-cadherin and the polyclonal antibody against N… CONTINUE READING