Alteration in keratinocyte ganglioside content in basal cell carcinomas.

@article{Paller1992AlterationIK,
  title={Alteration in keratinocyte ganglioside content in basal cell carcinomas.},
  author={Amy S Paller and S L Arnsmeier and June K Robinson and Eric G. Bremer},
  journal={The Journal of investigative dermatology},
  year={1992},
  volume={98 2},
  pages={
          226-32
        }
}
We examined the ganglioside content of normal human keratinocytes and basal cell carcinomas (BCC). The total ganglioside content of the epidermis was 0.098 +/- 0.01 microgram lipid-bound sialic acid/mg dry weight. GM3 was the predominant ganglioside of epidermis. GM2 and GD3 were also found in significant amounts. Polysialylated gangliosides were identified in only small amounts. In contrast to all other body locations, breast epidermis showed large amounts of GM1. The total ganglioside content… CONTINUE READING

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Amy S. PalIer, Sheryl, Arnsmeier, Maira Alvarez-Franco, Eric G. Bremer
  • 2010
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