Alteration in inflammatory mediators in seriously eye-injured war veterans, long-term after sulfur mustard exposure.

@article{Ghasemi2019AlterationII,
  title={Alteration in inflammatory mediators in seriously eye-injured war veterans, long-term after sulfur mustard exposure.},
  author={Hassan Ghasemi and Mohammad Ali Javadi and Sussan Kaboudanian Ardestani and Mahmoud Mahmoudi and Shahryar Pourfarzam and Mohammad Reza Vaez Mahdavi and Mohammad Ebrahim Yarmohammadi and A Baradaran-rafii and Khosrow Jadidi and Shamsa Shariatpanahi and Maryam Rastin and Fatemeh Heidary and Maliheh Safavi and Ensie sadat Mirsharif and Zahra Nasiri and Tooba Ghazanfari},
  journal={International immunopharmacology},
  year={2019},
  pages={
          105897
        }
}
BACKGROUND Sulfur mustard (SM) exposure produces extensive systemic and ocular adverse effects on the victims. One of the most important effects is immunological insults that can lead to other organ damages, including the eyes. METHODS In this descriptive study, 128 SM-exposed veterans with severe eye injury were compared with 31 healthy controls. Tear levels of tumor necrosis factor (TNF)-α and serum concentrations of interleukin (IL)-1α, IL-1β, IL1Ra, IL-6, TNF-α, granulocyte-macrophage… 
2 Citations
Therapeutic measures for sulfur mustard-induced ocular injury.
TLDR
This review focuses on treatment experience carried out in humans and studied in animal models, for both SM-induced ocular acute injury and late pathology, and investigates the potential of additional pharmacological and biological treatments or advanced cellular and molecular biology methods to serve as novel therapeutic measures and techniques for this complicated ocular injury.
Occupational Exposures and Environmental Health Hazards of Military Personnel
TLDR
It is indicated that only studies which analyzed epidemiological and molecular biomarkers in both exposed and control groups would provide evidence-based conclusions on exposure and disease risk in military personnel.

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