Alprazolam in the treatment of premenstrual syndrome. A double-blind, placebo-controlled trial.

@article{Schmidt1993AlprazolamIT,
  title={Alprazolam in the treatment of premenstrual syndrome. A double-blind, placebo-controlled trial.},
  author={Peter J. Schmidt and Gary Grover and David R Rubinow},
  journal={Archives of general psychiatry},
  year={1993},
  volume={50 6},
  pages={467-73}
}
OBJECTIVE To evaluate the efficacy of alprazolam in the treatment of premenstrual syndrome. DESIGN A randomized, double-blind, placebo-controlled, crossover trial of alprazolam during eight menstrual cycles. SETTING Outpatient clinic at the National Institute of Mental Health, Bethesda, Md. PARTICIPANTS Twenty-two women with prospectively confirmed premenstrual syndrome entered this study. All subjects were either self-referred or were referred by their physicians. All reported having… CONTINUE READING