Alprazolam dependence in seven patients.

  title={Alprazolam dependence in seven patients.},
  author={Stefan Juergens and Robert M. Morse},
  journal={The American journal of psychiatry},
  volume={145 5},
The authors report on seven patients who met the DSM-III-R criteria for psychoactive substance (alprazolam) dependence. All had withdrawal symptoms, six demonstrated tolerance, and at least four had substantial social or occupational impairment secondary to drug use. All seven patients had begun taking alprazolam as treatment for anxiety or depression. Six patients abused other drugs or alcohol, either in the past or concurrently. Doses of alprazolam ranged from 2 to 12 mg/day, and duration of… CONTINUE READING

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