Alprazolam and Diazepam in the Treatment of Generalized Anxiety

  title={Alprazolam and Diazepam in the Treatment of Generalized Anxiety},
  author={R. Elie and Y. Lamontagne},
  journal={Journal of Clinical Psychopharmacology},
  • R. Elie, Y. Lamontagne
  • Published 1984
  • Psychology, Medicine
  • Journal of Clinical Psychopharmacology
  • In a 4-week double-blind study comparing alprazolam with diazepam treatments, 48 outpatients suffering from mild to moderate generalized anxiety were evaluated after a 5-day placebo washout, and then after 1, 2, and 4 weeks of treatment. The optimal therapeutic doses without excessive sedation averaged 2 mg for alprazolam and 15.8 mg for diazepam. Results from the Hamilton Anxiety Rating Scale, the Clinical Global Impression Scale, a behavior checklist questionnaire, and a symptomatic patients… CONTINUE READING
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