Alphavirus nucleocapsid protein contains a putative coiled coil alpha-helix important for core assembly.

Abstract

The alphavirus nucleocapsid core is formed through the energetic contributions of multiple noncovalent interactions mediated by the capsid protein. This protein consists of a poorly conserved N-terminal region of unknown function and a C-terminal conserved autoprotease domain with a major role in virion formation. In this study, an 18-amino-acid conserved… (More)

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