Alpha2delta ligands, gabapentin, pregabalin and mirogabalin: a review of their clinical pharmacology and therapeutic use

@article{Calandre2016Alpha2deltaLG,
  title={Alpha2delta ligands, gabapentin, pregabalin and mirogabalin: a review of their clinical pharmacology and therapeutic use},
  author={Elena P Calandre and Fernando Rico-Villademoros and Mahmoud Slim},
  journal={Expert Review of Neurotherapeutics},
  year={2016},
  volume={16},
  pages={1263 - 1277}
}
ABSTRACT Introduction: The first two alpha2delta ligands – gabapentin (GBP) and pregabalin (PGB) – were initially synthesized as antiepileptics; however, they were later also found to be useful for the treatment of additional conditions. Areas covered: Relevant publications describing potential underlying mechanisms, clinical pharmacokinetics/pharmacokinetics, and clinical efficacy and safety of these drugs in various disease conditions were searched in PubMed and Scopus and included in this… Expand
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TLDR
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Non-medical Use of Prescription Gabapentinoids (Gabapentin and Pregabalin) in Five European Countries
TLDR
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