Alpha1-antitrypsin deficiency.

  title={Alpha1-antitrypsin deficiency.},
  author={Peter C G\otzsche and Helle Krogh Johansen},
  journal={The New England journal of medicine},
  volume={361 21},
  pages={2101-2; author reply 2102}
n engl j med 361;21 november 19, 2009 2101 conservative conclusion is consistent with the trend toward an increased risk of pulmonary em­ bolism with apixaban; we calculate that the rela­ tive risk is 2.28 (95% CI, 0.97 to 5.39; P = 0.06 by the chi­square test). The timing of the first apixa­ ban administration (a mean [±SD] of 20.3±3.5 hours postoperatively in the Apixaban Dose Orally vs. Anticoagulation with Enoxaparin 2 [ADVANCE­1] study; number, NCT00371683) or… CONTINUE READING