Alpha1-antitrypsin deficiency - diagnostic testing and disease awareness in Germany and Italy.

  title={Alpha1-antitrypsin deficiency - diagnostic testing and disease awareness in Germany and Italy.},
  author={Timm Greulich and Stefania Ottaviani and Robert Bals and Philipp Moritz Lepper and Claus F Vogelmeier and Maurizio Luisetti and Ilaria Ferrarotti},
  journal={Respiratory medicine},
  volume={107 9},
BACKGROUND Alpha1-antitrypsin (AAT) deficiency, although largely under-diagnosed, is the underlying cause of approximately 1% of COPD cases. Lack of awareness leads to long delays in diagnostic testing. Subsequently, lifestyle and treatment choices with potentially positive effects on prognosis may be postponed. METHODS Data on the testing and diagnostic practices for AAT deficiency were derived from the University of Pavia, Italy, and the University of Marburg, Germany. In addition, a survey… CONTINUE READING
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